Juan Cebral Professor of Computational Fluid Dynamics Office: Telephone: Fax: E-mail: Homepage: CV: Research 1, Room 342 703-993-4078 703-993-9300 jcebral@gmu.edu http://www.scs.gmu.edu/~jcebral http://www.scs.gmu.edu/~jcebral/vitae/CV-full.pdf Mailing Address Center for Computational Fluid Dynamics Department of Computational and Data Sciences College of Science George Mason University 4400 University Dr., MSN 6A2 Fairfax, Virginia 22030

Current Research Interests

The focus of our research is in image-based patient-specific computational fluid dynamics (CFD) modeling of blood flows. In particular, we concentrate on blood flows to the brain. This research involves: a) the development of computational methods and tools for patient-specific modeling from medical images, and b) the application of these models to the study of cerebrovascular diseases. The objective of our research is to connect hemodynamic variables obtained from patient-specific models to clinical events in order to better understand the disease processes for improving patient evaluation and treatment. In particular, we are studying cerebral aneurysms which are the leading cause of hemorrhagic strokes, a very devastating event. This is a highly multi-disciplinary field that involves: medical image analysis, geometry modeling, grid generation, numerical solution of partial differential equations, computer graphics and visualization, as well as anatomy and physiology, biofluids, biomechanics, and vascular biology. For this reason, this work is carried out in close collaboration with researchers and clinicians from other institutions. We work very closely with clinicians from the Interventional Neuroradiology unit at Inova Fairfax Hospital.

This work has been supported by grants from the Whitaker Foundation, Philips Medical Systems, the American Heart Association, Boston Scientific and the National Institutes of Health.

• Ph.D. 1996 - George Mason University, Computational Sciences and Informatics

• M.Sc. 1991 - University of Buenos Aires, Physics

Courses Taught

• CSI 701: Foundations of Computational Sciences
  
• CSI 720: Fluid Mechanics
  
• CSI 796: Directed Reading and Research
                Brain Perfusion Models
                Computational Hemodynamics
                Arterial Tree Models
  
• NEUR 703: Laboratory Rotation and Reading
                    Brain Vascular Trees
  

Recent Publications

• Cebral JR, Pergolizzi R, Putman CM, “Computational Fluid Dynamics Modeling of Intracranial Aneurysms: Qualitative Comparison with Conventional Angiography”, Academic Radiology, 14(7): 804-813, 2007.
  

• Castro, M.A., C.M. Putman, and J.R. Cebral, “Computational fluid dynamics modeling of intracranial aneurysms: effects of parent artery segmentation on intra-aneurysmal hemodynamcis”. American Journal of Neuroradiology, 27: 1703-1709, 2006.
  

• Castro MA, Putman CM, Cebral JR, “Patient-Specific Computational Modeling of Cerebral Aneurysms with Multiple Avenues of Flow from 3D Rotational Angiography Images”, Academic Radiology, 13(7): 811-821, 2006.
  

• Cebral JR, Castro MA, Burgess JE, Pergolizzi R, Putman CM, “Characterization of Cerebral Aneurysm for Assessing Risk of Rupture Using Patient-Specific Computational Hemodynamics Models” American Journal of Neuroradiology, 26: 2550-2559, 2005.
  

• Cebral JR, Castro MA, Appanaboyina S, Putman CM, Millan D, Frangi A, “Efficient Pipeline for Image-Based Patient-Specific Analysis of Cerebral Aneurysm Hemodynamics: Technique and Sensitivity”, IEEE Transactions on Medical Images 24(4): 457-467, special issue on vascular imaging, April 2005